Saturday 30 December 2017

DNA transcription

Transcription is a process in which DNA get transcribed to RNA or information presents in DNA get transferred to RNA and it is ready to be translated.

This process takes place in several steps : 

Initiation, elongation and termination. 

Initiation : in initiation an enzyme called DNA dependent RNA polymerase gets attached or binds at specific location on DNA and starts the process of transcription

Note : DNA dependent RNA polymerase in this case is Pol II (core-enzyme) and works with Sigma factor which helps in recognition of specific site to bind with DNA

Core-enzyme + Sigma factor = holoenzyme

Elongation : Once the initiation is completed Sigma factor gets released from holoenzyme and Core-enzyme continuously transcribe the DNA

Termination : Once the whole gene is transcribed at the end there are specific sequence called as stop codon and Core-enzyme gets de-attached from DNA and transcription process gets over.

No comments:

Post a Comment